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CALHOUN COUNTY, Miss. — At least three adults died when a Mississippi school bus full of high school students collided head-on with an 18-wheeler Tuesday afternoon in Calhoun County, NBC station WTVA reported.

At least 60 others were injured, officials said.

The big-rig driver was among the dead, Mississippi Department of Public Safety spokesman John Kalahar told The Associated Press. The two adults were on the bus, NBC News said.

Calhoun County Coroner Jerry Fleming told NBC News two buses were involved. The semitrailer appeared to have sideswiped one and hit the other head-on, he said.

The accident happened at a bridge along Highways 8 and 9, south of Calhoun City, officials told WTVA.

The school bus from Ackerman High School in Choctaw County was returning from a senior trip to the University of Mississippi in Oxford, said NBC station WCM.

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