The high altitude of Denver’s Mile High Stadium, could possibly have a negative affect on Clark’s condition and he previously had to have a gall bladder removed and lost 30 pounds to Sickle Cell after a 2007 game in Denver.
But the CDC cautions that those with sickle cell trait can experience complications during both athletic activity and when at high altitudes. Denver, known as the Mile-High City, is 5,280 feet above sea level. Pittsburgh is about 770 feet above sea level.
Clark has been the Steelers’ busiest defender this season, according to ESPN.com. He has been on the field for 1,009 snaps this season, or 98.7% of the team’s defensive plays. He led the team with 100 tackles.