Top Ten Videos to watch

Hillary Clinton Meets With DC Mayor And DC Representative At Coffee Shop
crime scene
Vote
Studio Portrait of Two Young Women Back to Back, One With a Tattoo
Mamie Till and Emmett Till
GOP Redistricting Plot To Unseat Rep. Corrine Brown Exposed
Protests Break Out In Charlotte After Police Shooting
'Keep the Vote Alive!' March Commemorates Civil Rights Act
White man shooting
Gun Violence Continues To Plague Chicago, Over 1,000 Shootings For Year To Date
HS Football
Gun Violence Continues To Plague Chicago, Over 1,000 Shootings For Year To Date
Police Line
US-POLITICS-OBAMA
2016 Republican National Convention
44th NAACP Image Awards - Show
MD Primary
Premiere Of OWN's 'Queen Sugar' - Arrivals
Democratic National Convention
US-VOTE-REPUBLICANS-TRUMP
Los Angeles Rams v San Francisco 49ers
US-POLICE-RACISM-UNREST
Protesters Demonstrate Against Donald Trump's Visit To Flint Michigan
President Obama Speaks On The Economy In Brady Press Briefing Room
Lil Wayne
Construction Continues On The National Museum of African American History To Open In 2016
Preacher Preaching the Gospel
Hillary Clinton Campaigns In Louisville, Kentucky
Miami Dolphins v Seattle Seahawks
US-VOTE-DEMOCRATS-CONVENTION
Leave a comment

Iron overload is an excess (too much) iron in the body. Excess iron in vital organs, even in mild cases of iron overload, increases the risk for liver disease (cirrhosis, cancer), heart attack or heart failure, diabetes mellitus, osteoarthritis, osteoporosis, metabolic syndrome, hypothyroidism, hypogonadism, numerous symptoms and in some cases premature death.

Here are the facts you need to know about this potentially-dangerous condition:

What is it?

Iron overload is characterized by an elevated serum ferritin with a normal transferrin-iron saturation percentage. People with iron overload syndrome will likely also have an elevated GGT (liver enzyme) possibly due to a fatty liver. Individuals with DIOS are helped by phlebotomy, diet and exercise. The FeGGT test is helpful in determining the iron status and GGT status.

Iron mismanagement resulting in overload can accelerate such neurodegenerative diseases as Alzheimer’s, early-onset Parkinson’s, Huntington’s, epilepsy and multiple sclerosis.

How do you get it?

Iron overload can be inherited (genetic) or acquired by receiving numerous blood transfusions, getting iron shots or injections, or consuming high levels of supplemental iron. Some of the genetic disorders that result in iron overload include are hereditary hemochromatosis (all types), African iron overload, sickle cell disease, thalassemia, X-linked sideroblastic anemia, enzyme deficiencies (pyruvate kinase; glucose-6-phosphate dehydrogenase) and very rare protein transport disorders aceruloplasminemia and atransferrinemia.

None of these conditions should be confused with polycythemia vera (PV), which is not an iron disorder, but a condition where the bone marrow produces too many blood cells (red, white and platelet). People with PV have abnormally high hemoglobin and are at risk for a stroke and progressing to acute myelogenous leukemia (AML).  Part of the therapy for PV is phlebotomy.

What are the symptoms?
 


Symptoms resulting from iron overload include:

▪ Chronic fatigue

▪ Joint pain

▪ Abdominal pain

▪ Liver disease (cirrhosis, liver cancer)

▪ diabetes mellitus

▪ irregular heart rhythm

▪ heart attack or heart failure

▪ skin color changes (bronze, ashen-gray green)

▪ loss of period

▪ loss of interest in sex

▪ osteoarthritis

▪ osteoporosis

▪ hair loss

▪ enlarged liver or spleen

▪ impotence

▪ infertility

▪ hypogonadism

▪ hypothyroidism

▪ hypopituitarism

▪ depression

▪ adrenal function problems

▪ early onset neurodegenerative disease

▪ elevated blood sugar

▪ elevated liver enzymes

▪ elevated iron (serum iron, serum ferritin)

Treatment Options

The treatment for iron overload is iron reduction therapy. A person’s hemoglobin is key in the physician’s decision of iron reduction therapy. If the patient’s hemoglobin level is sufficient to tolerate blood removal (phlebotomy), the doctor can provide either an order for therapeutic phlebotomies or can recommend that a patient routinely donate blood. When a patient’s hemoglobin is too low for phlebotomy, iron reduction  will likely require iron-chelation, which is the removal of iron using specific drugs. In some situations the physician may use a combination of these two therapies.

Also On News One:
comments – Add Yours